Review Identifies 140 Controlled Clinical Trials Related to Cannabis

Marijuana researchScientists have conducted over 140 controlled clinical trials since 1975 assessing the safety and efficacy of whole-plant cannabis or specific cannabinoids, according to a new literature review published in the journal Critical Reviews in Plant Sciences.

A pair of German researchers identified 140 clinical trials involving an estimated 8,000 participants. Of these, the largest body of literature focused on the use of cannabis or cannabinoids in the treatment of chronic or neuropathic pain. Authors identified 35 controlled studies, involving 2,046 subjects, assessing the use of marijuana or cannabinoids in pain management. In January, the National Academy of Sciences acknowledged that “conclusive or substantial evidence” exists for cannabis’ efficacy in patients suffering from chronic pain.

Cannabinoids have also been well studied as anti-emetic agents and as appetite stimulants. Researchers identified 43 trials evaluating marijuana or its components for these purposes, involving total 2,498 patients. They also identified an additional 14 trials examining the role of cannabis or cannabis-derived extracts in the treatment of multiple sclerosis.

Researchers also identified several additional trials evaluating the use of cannabis or cannabinoids for Crohn’s disease, Tourette’s syndrome, Parkinson’s disease, glaucoma, epilepsy, and various other indications.

A 2014 study published in the Journal of the American Medical Association reported that new drugs typically gain FDA approval on the basis of one or two pivotal clinical trials.

Full text of the study, “Medicinal uses of marijuana and cannabinoids,” appears online here.

Take Action This Memorial Day

for_painVeterans have served our nation honorably. So this Memorial Day, why is the federal government denying those veterans suffering from debilitating ailments like chronic pain and PTSD access to the therapeutic effects of marijuana?

Presently, V.A. doctors residing in states where medical cannabis is legal remain forbidden from providing the paperwork necessary to complete a medical marijuana recommendation — thus forcing military veterans to seek the advice of an expensive, private, out-of-network physician.

Recently introduced legislation, HR 1820, ends this prohibition.

Send a message to your member of Congress and tell them to support veterans by supporting HR 1820. 

Last year, majorities in both the US House and Senate voted to include similar language as part of the Fiscal Year 2017 Military Construction, Veterans Affairs and Related Agencies Appropriations Bill. However, Republicans sitting on the House Appropriations Committee elected to remove the language from the bill during a concurrence vote.

Our veterans deserve the option to legally access a botanical product that is objectively safer than the litany of pharmaceutical drugs it stands to replace.

Tell your Representative, don’t play politics with the health of our veterans.

Given the choice, patients will reach for cannabis over prescribed opioids

Chronic pain sufferers and those taking mental health meds would rather turn to cannabis instead of their prescribed opioid medication, according to new research.

NORML Responds To National Academy of Sciences’ Marijuana Report

for_painThe National Academy of Sciences, Engineering, and Medicine released a comprehensive report today acknowledging that “conclusive or substantial evidence” exists for cannabis’ efficacy in patients suffering from chronic pain, and sharply criticized longstanding federal regulatory barriers to marijuana research – in particular “the classification of cannabis as a Schedule I substance” under federal law.

Authors of the report also addressed various aspects of marijuana’s effect on health and safety, acknowledging that the substance may pose certain potential risks for adolescents, pregnant women, and for those who may be driving shortly after ingesting cannabis. In each of these cases, these risks may be mitigated via marijuana regulation and the imposition of age restrictions in the marketplace.

Commenting on the report, NORML Deputy Director Paul Armentano said:

“The National Academy of Science’s conclusions that marijuana possesses established therapeutic utility for certain patients and that it possesses an acceptable safety profile when compared to those of other medications or recreational intoxicants are not surprising. This evidence has been available for some time, yet for decades marijuana policy in this country has largely been driven by rhetoric and emotion, not science and evidence.

“A search on PubMed, the repository for all peer-reviewed scientific papers, using the term ‘marijuana’ yields over 24,000 scientific papers referencing the plant or its biologically active constituents — a far greater body of literature than exists for commonly consumed conventional drugs like Tylenol, ibuprofen, or hydrocodone. Further, unlike modern pharmaceuticals, cannabis possesses an extensive history of human use dating back thousands of years, thus providing society with ample empirical evidence as to its relative safety and efficacy.

“Today, 29 states and Washington, DC permit physicians to recommend marijuana therapy. Some of these state-sanctioned programs have now been in place for nearly two decades. Eight states also permit the regulated use and sale of cannabis by adults. At a minimum, we know enough about cannabis, as well as the failures of cannabis prohibition, to regulate its consumption by adults, end its longstanding criminalization, and to remove it from its Schedule I prohibitive under federal law.”

The report marks the first time since 1999 that the National Academy of Sciences has addressed issues surrounding marijuana and health. Authors reviewed over 10,000 scientific abstracts in their preparation of the new report.

You can read the full report here.

Cannabis: Non-addictive pathway to pain relief?

New research suggests an avenue for developing treatments for chronic pain that harness the medicinal properties of cannabis while minimizing the threat of addiction. Therapeutics that target the endocannabinoid system might produce pain relief with fewer side effects compared with opioids.

Compound suggests chronic pain treatment without opioid or medical marijuana side effects

Neuroscientists have found evidence that the brain’s cannabis receptors may be used to treat chronic pain without the side effects associated with opioid-based pain relievers or medical marijuana.

How the federal government limits valid scientific research on Cannabis sativa

The use of medical marijuana for millions of patients suffering from a wide range of health conditions and the subsequent therapeutic benefits has long been documented. Cannabis sativa can benefit patients suffering from a wide range of conditions, including cancer, epilepsy, chronic pain, and post-traumatic stress disorder. So given all the health benefits for people experiencing debilitating health issues, why does the federal government continue to stifle valid, externally valid scientific research on Cannabis sativa?

Experts off guidance on medical marijuana for pain

Marijuana often is used to self treat chronic pain and, with 24 states legalizing medical use of the herb, experts have published guidance for physicians caring for patients who use cannabis. The paper also identified opportunities for future research required to better understand the health effects of cannabinoids.

Many patients abusing drugs, alcohol are self-medicating chronic pain

With opioid addiction and prescription drug abuse considered one of the biggest public health threats of our time in the US, many are asking why so many Americans are struggling with addiction to illegal drugs and prescription medications. New research suggests that chronic pain may be part of the answer.

Medical Kush Beach Club Tour with Roxy on hashbartv

www.hashbar.tv Come inside the Medical Kush Beach Club in Venice CA with Roxy from Barracuda and Sean Kush as they look at how to get your medication and what types of marijuana helps chronic pain. Also we talk with a couple of the regulars as they describe their use of medical marijuana. For more episodes go to http For information about the Medical Kush Beach Clib go To www.medicalkushbeachclub.com

Leiden University is home to pharmacology studies by Arno Hasekamp on marijuana to discover the properties and chemistry that make pot what it is.
Video Rating: 5 / 5

Enterhealth Appoints Dr. Carlos Tirado as Chief Medical Officer


Dallas, TX (PRWEB) January 15, 2010

Enterhealth, an addiction disease management company, has appointed Carlos Tirado, MD, MPH, as chief medical officer. Bringing more than 10 years of substance abuse treatment, research and teaching experience to Enterhealth, Dr. Tirado will oversee client medical care at Enterhealth?s Life Recovery Center, a private residential treatment center located just north of Dallas.

A Dallas native, Dr. Tirado is board certified in general psychiatry and addiction medicine. In addition to his full-time position with Enterhealth, he also serves as a clinical assistant professor of psychiatry at the University of Texas Southwestern Medical Center at Dallas. Additionally, Dr. Tirado is a coalition member of the Dallas Area Prevention Partnership and is a founding member of the Dallas Coalition for Treatment Improvement. Dr. Tirado?s previous clinical work includes the last four years as medical director of Nexus Recovery Center in Dallas.

?Enterhealth has gained a highly respected professional in Dr. Tirado, who is committed to providing a full continuum of care to our clients with the most advanced, individualized treatment for addiction, said David Kniffen Jr., president of Enterhealth. ?We are extremely fortunate that the success we have experienced since opening our doors in December 2008, combined with the increased demand for our latest science-based treatments, has afforded us the opportunity to grow our clinical expertise and add on-site medical professionals, like Dr. Tirado, who provide dual diagnosis assessments and success plans for our clients? individual needs.?

?I am thrilled to join the Enterhealth team because they have a progressive, disease-based approach that is found in only a very small, elite group of science-based treatment providers in the United States,? said Dr. Tirado. ?As a researcher, clinician and psychiatrist, I am convinced that outdated approaches for substance dependence recovery must be replaced with advanced, evidence-based approaches that yield more promising results, which is the foundational approach at Enterhealth.?

Dr. Tirado has conducted health disparities research on Hepatitis C treatment in veterans and adolescent addiction supported by the National Institute on Drug Abuse, the National Center on Minority Health and Health Disparities, and the Robert Wood Johnson Foundation. His clinical work has focused on medication assisted treatment of chronic addiction, treatment of chronic pain and co-morbid addiction, treatment of co-occurring psychiatric disorders (dual diagnosis), training addiction professionals and implementation of evidence-based behavioral therapies. Dr. Tirado has published work in the areas of chronic pain, marijuana dependence, opiate dependence, alcohol dependence and cocaine dependence.

After earning a Bachelor of Arts in biology and liberal arts from the University of Dallas, Dr. Tirado earned a Doctorate of Medicine from the University of Texas Health Science Center in Houston and Community Health Promotion degree from University of Texas School of Public Health. He trained as a resident in psychiatry at UT Southwestern and Parkland Memorial Hospital after which he trained in addiction psychiatry under a fellowship at the University of Pennsylvania Center for Studies on Addiction.

Dr. Tirado is a member of the American Society of Addiction Medicine (ASAM), College on Problem of Drug Dependence (CPDD), American Academy of Addiction Psychiatrists (AAAP), North and Central Texas Clinical and Translational Services Initiative (NCTCTSI) and Community Health Research Initiative (CHRI) and is certified on the American Board of Psychiatry and Neurology.

About Enterhealth

Headquartered in Dallas, Texas, Enterhealth, was founded by a team of distinguished addiction recovery experts and professionals who hold a vision to provide world-class, affordable and accessible addiction treatment resources and educational tools to treat the chronic brain disease of addiction.

NOTE TO EDITORS: Dr. Tirado?s photograph and more extensive biographical information is available upon request. Please call Martha Cook or Scott Tims at 214-378-7970 x240/x278.

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Medical cannabis provides dramatic relief for sufferers of chronic ailments, Israeli study finds

Though still controversial, medical cannabis has been gaining ground as a valid therapy for cancer, PTSD, and chronic pain. Now a specialist says that residents of an Israel nursing home experienced dramatic physical and mental improvements following cannabis therapy and that the therapy significantly reduced the need for chronic medications for many of them.

San Jose 420 Evaluations Outlines Recent Findings on Marijuana?s Usefulness in Treating Chronic Pain


San Jose, CA (Vocus/PRWEB) March 25, 2011

Medical marijuana advocates have known for a long time that cannabis is an effective treatment for their patients who suffer from chronic pain, and recently released scientific studies from UC San Diego?s Center for Medical Cannabis Research support this claim with solid evidence. San Jose 420 Evaluations, a medical marijuana dispensary, explains chronic pain and the various recent studies? conclusions about how marijuana helps alleviate its symptoms.

Pain, a signal from the nervous system to the brain that alerts it to possible injury, can be very useful. Chronic pain, wherein according to the National Institute for Health, ?pain signals keep firing in the nervous system for weeks, months, even years,? can cause terrible suffering in people?s daily lives. According to the American Pain Foundation, 50 million Americans suffer from persistent pain each year, causing sleep difficulties, absenteeism at work, social effects and other related hardships. According to an article in TIME Magazine, $ 50 billion is spent on it annually in this country. Chronic pain may result from an injury, come with age, or be associated with other ailments.

The National Pain Foundation explains that the human body contains cannaboid receptors in the brain, spinal cord and immune system. Cannaboids, including tetrahydrocannabinol (THC), a chemical compound found in marijuana, react with the cannaboid receptors to alleviate symptoms of pain.

Recent controlled studies have demonstrated marijuana?s effectiveness on treating chronic pain associated with a number of other diseases. UC San Diego?s Center for Medicinal Cannabis Research found that, among other things,

Illinois Cannabis Patient Julie

It has been scientifically proven that cannabis has a wide range of therapeutic uses, including relieving nausea, increasing appetite, reducing muscle spasms, and relieving chronic pain. Two former surgeons general, Joycelyn Elders and Jesse L. Steinfeld, have supported the medical use of cannabis. Thousands of patients and their doctors have found cannabis to be useful in treating the symptoms of AIDS, cancer, multiple sclerosis, glaucoma, and other serious conditions. Please support our efforts to pass a medical cannabis law in the state of Illinois.

Medical Marijuana Cooking 101

Patients Without Time presents, Medical Marijuana Cooking 101, which offers a lesson in cooking for medical marijuana patients. Medicine that’s yummy, too. For high quality playback: www.isseiproductions.com

Arizona Medical Marijuana is now legal and by far the most common indication in other states is chronic pain. Will this be the predominant reason to obtain an Arizona Marijuana ID Card? Arizona MMC discusses what we know about marijuana’s effects on chronic pain. Call Toll Free (855) AZ-IDCARD for an evaluation TODAY! www.medicalmarijuanacertificationsarizona.com

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